cool...so basically, the typical "dissensian on holiday", then? ;-)
will get back to you with the eat/drink scenario (i'm sure others will chime in as well), but on the music store front, that's easy: it sucks! we're down to hardly anywhere anymore in manhattan:
-- turntable labs, small, most dance vinyl (120 east 7th between 1st ave-ave a)
-- other music (
www.othermusic.com, 15 east 4th st between broadway/lafayette) is a small store with decent indie, electronic, The Wire-type stuff, although they've cut back on stock and increased used cds lately.
-- there are a couple of places on st. mark's place (which is actually east 8th st bet. 3rd ave and avenue a) that aren't particularly good.
-- the relocated kim's video (w/cds and some vinyl) on 1st avenue bet. 7th/st. mark's).
-- i've sometimes found ok used cds at academy records (12 west 18th bet. 5th/6th ave), big on jazz and classical.
can always to a quick side trip to williamsburg, brooklyn, a short 5-minute subway ride on the eastbound L train to the first stop in brooklyn (bedford avenue). it's kinda of annoying the same way i imagine hoxton/shoreditch and thereabouts can be, lots of slumming faux-hipster types, but also lots of bars/cafes/stores and a few decent record shops:
-- earwax records, run by wfmu dj fabio, 218 bedford ave.
-- soundfix, moving this week, opening new story on september 1 at corner of Berry/north 11th st)
-- another academy records at 96 north 6th st.
re: music venues/bands, you'll have to check local listings when in town.
just off the top of my head, more to come.