Craner - I haven't read that much Roth (loved Portnoy, was steadily bored by American Pastoral) but I think 'Everyman' is quite interesting. It's about the last year or so of a man's life - his diminishing health, his growing terror. Reminded me of Tolstoy's 'Death of Ivan Ilyich', but with a decidedly atheistic mental redemption at the climax. It's so pared down that I think it avoids the rhetorically shrill, chest-beating quality of some of his other stuff, which I find a bit hard to take. But then there aren't so many great dick jokes either...
My Mum absolutely loves his stuff and she recommended 'Patrimony', which is about his father. I think 'Goodbye Columbus', a collection of short stories, is supposed to be good too.