All I know, is that Atomoxetine is one of the only four presciptions I'm currently taking, besides Pramipexole for restless leg, that I feel like actually do something - and this goes back to being prescribed something or other for the last 35+ years since my mid-late teens (including drugs I feel like they carelessly experimented on me with in mental hospitals - those definitely did something, but not in a good way)
OTOH, some of the medication I've taken for depression and/or anxiety over the years, although I don't notice the effects, other people sometimes say they do.
Although I did notice an effect one time when I stopped taking wellbutrin - I couldn't get Don't Fear the Reaper out of my head.
Or whatever experiment it was that I volunteered for at a hospital in Seattle where they were testing some kind of drug for autism related disorders, I didn't notice a difference, but my sister who was living near me at the time said she noticed some kind of difference, so who knows?